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BRCA1 Induces Major Energetic Metabolism Reprogramming in Breast Cancer Cells
The hypermetabolic nature of cancer cells and their increased reliance on “aerobic glycolysis”, as originally described by Otto Warburg and colleagues, are considered metabolic hallmarks of cancer cells. BRCA1 is a major tumor suppressor in breast cancer and it was implicated in numerous pathways re...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4092140/ https://www.ncbi.nlm.nih.gov/pubmed/25010005 http://dx.doi.org/10.1371/journal.pone.0102438 |