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Influenza A Virus Host Shutoff Disables Antiviral Stress-Induced Translation Arrest

Influenza A virus (IAV) polymerase complexes function in the nucleus of infected cells, generating mRNAs that bear 5′ caps and poly(A) tails, and which are exported to the cytoplasm and translated by host machinery. Host antiviral defences include mechanisms that detect the stress of virus infection...

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Detalles Bibliográficos
Autores principales: Khaperskyy, Denys A., Emara, Mohamed M., Johnston, Benjamin P., Anderson, Paul, Hatchette, Todd F., McCormick, Craig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4092144/
https://www.ncbi.nlm.nih.gov/pubmed/25010204
http://dx.doi.org/10.1371/journal.ppat.1004217