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Influenza A Virus Host Shutoff Disables Antiviral Stress-Induced Translation Arrest
Influenza A virus (IAV) polymerase complexes function in the nucleus of infected cells, generating mRNAs that bear 5′ caps and poly(A) tails, and which are exported to the cytoplasm and translated by host machinery. Host antiviral defences include mechanisms that detect the stress of virus infection...
Autores principales: | Khaperskyy, Denys A., Emara, Mohamed M., Johnston, Benjamin P., Anderson, Paul, Hatchette, Todd F., McCormick, Craig |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4092144/ https://www.ncbi.nlm.nih.gov/pubmed/25010204 http://dx.doi.org/10.1371/journal.ppat.1004217 |
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