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Tocilizumab, a Proposed Therapy for the Cachexia of Interleukin6-Expressing Lung Cancer

BACKGROUND: We previously reported the role of IL-6 in a murine model of cancer cachexia and currently documented a patient in whom tocilizumab, anti-IL-6 receptor antibody, dramatically improved cachexia induced by IL-6 over-expressing lung cancer. Despite this potential to alleviate cancer cachexi...

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Detalles Bibliográficos
Autores principales: Ando, Katsutoshi, Takahashi, Fumiyuki, Kato, Motoyasu, Kaneko, Norihiro, Doi, Tokuhide, Ohe, Yuichiro, Koizumi, Fumiaki, Nishio, Kazuto, Takahashi, Kazuhisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4092149/
https://www.ncbi.nlm.nih.gov/pubmed/25010770
http://dx.doi.org/10.1371/journal.pone.0102436