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Distribution of segmental duplications in the context of higher order chromatin organisation of human chromosome 7

BACKGROUND: Segmental duplications (SDs) are not evenly distributed along chromosomes. The reasons for this biased susceptibility to SD insertion are poorly understood. Accumulation of SDs is associated with increased genomic instability, which can lead to structural variants and genomic disorders s...

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Detalles Bibliográficos
Autores principales: Ebert, Grit, Steininger, Anne, Weißmann, Robert, Boldt, Vivien, Lind-Thomsen, Allan, Grune, Jana, Badelt, Stefan, Heßler, Melanie, Peiser, Matthias, Hitzler, Manuel, Jensen, Lars R, Müller, Ines, Hu, Hao, Arndt, Peter F, Kuss, Andreas W, Tebel, Katrin, Ullmann, Reinhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4092221/
https://www.ncbi.nlm.nih.gov/pubmed/24973960
http://dx.doi.org/10.1186/1471-2164-15-537