PKC-dependent Phosphorylation of the H1 Histamine Receptor Modulates TRPC6 Activity

Transient receptor potential canonical 6 (TRPC6) is a cation selective, DAG-regulated, Ca(2+)-permeable channel activated by the agonists of G(q)-protein-coupled heptahelical receptors. Dysfunctions of TRPC6 are implicated in the pathogenesis of various cardiovascular and kidney conditions such as v...

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Detalles Bibliográficos
Autores principales: Chen, Xingjuan, Egly, Christian, Riley, Ashley M., Li, Wennan, Tewson, Paul, Hughes, Thomas E., Quinn, Anne Marie, Obukhov, Alexander G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4092854/
https://www.ncbi.nlm.nih.gov/pubmed/24709960
http://dx.doi.org/10.3390/cells3020247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4092854/
https://www.ncbi.nlm.nih.gov/pubmed/24709960
http://dx.doi.org/10.3390/cells3020247

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