The Cytolethal Distending Toxin Effects on Mammalian Cells: A DNA Damage Perspective

The cytolethal distending toxin (CDT) is produced by many pathogenic Gram-negative bacteria and is considered as a virulence factor. In human cells, CDT exposure leads to a unique cytotoxicity associated with a characteristic cell distension and induces a cell cycle arrest dependent on the DNA damag...

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Detalles Bibliográficos
Autores principales: Bezine, Elisabeth, Vignard, Julien, Mirey, Gladys
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4092857/
https://www.ncbi.nlm.nih.gov/pubmed/24921185
http://dx.doi.org/10.3390/cells3020592

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4092857/
https://www.ncbi.nlm.nih.gov/pubmed/24921185
http://dx.doi.org/10.3390/cells3020592

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