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Mechanisms of Activation of Receptor Tyrosine Kinases: Monomers or Dimers
Receptor tyrosine kinases (RTKs) play essential roles in cellular processes, including metabolism, cell-cycle control, survival, proliferation, motility and differentiation. RTKs are all synthesized as single-pass transmembrane proteins and bind polypeptide ligands, mainly growth factors. It has lon...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4092861/ https://www.ncbi.nlm.nih.gov/pubmed/24758840 http://dx.doi.org/10.3390/cells3020304 |