Cargando…

Endosome-to-Plasma Membrane Recycling of VEGFR2 Receptor Tyrosine Kinase Regulates Endothelial Function and Blood Vessel Formation

Rab GTPases are implicated in endosome-to-plasma membrane recycling, but how such membrane traffic regulators control vascular endothelial growth factor receptor 2 (VEGFR2/KDR) dynamics and function are not well understood. Here, we evaluated two different recycling Rab GTPases, Rab4a and Rab11a, in...

Descripción completa

Detalles Bibliográficos
Autores principales: Jopling, Helen M., Odell, Adam F., Pellet-Many, Caroline, Latham, Antony M., Frankel, Paul, Sivaprasadarao, Asipu, Walker, John H., Zachary, Ian C., Ponnambalam, Sreenivasan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4092869/
https://www.ncbi.nlm.nih.gov/pubmed/24785348
http://dx.doi.org/10.3390/cells3020363