In silico comparative characterization of pharmacogenomic missense variants

BACKGROUND: Missense pharmacogenomic (PGx) variants refer to amino acid substitutions that potentially affect the pharmacokinetic (PK) or pharmacodynamic (PD) response to drug therapies. The PGx variants, as compared to disease-associated variants, have not been investigated as deeply. The ability t...

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Detalles Bibliográficos
Autores principales: Li, Biao, Seligman, Chet, Thusberg, Janita, Miller, Jackson L, Auer, Jim, Whirl-Carrillo, Michelle, Capriotti, Emidio, Klein, Teri E, Mooney, Sean D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4092878/
https://www.ncbi.nlm.nih.gov/pubmed/25057096
http://dx.doi.org/10.1186/1471-2164-15-S4-S4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4092878/
https://www.ncbi.nlm.nih.gov/pubmed/25057096
http://dx.doi.org/10.1186/1471-2164-15-S4-S4

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