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Intraventricular Topotecan for the Treatment of Neoplastic Meningitis: Five Case Studies

Many systemic cytotoxic agents cannot penetrate the blood-brain barrier. Because of this, in approximately 5% of cancer cases, metastatic disease is seen in the leptomeninges. Without treatment, patients with neoplastic meningitis (NM) generally survive for only a matter of weeks. In the treatment o...

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Detalles Bibliográficos
Autores principales: Walker, Julie, Schultz, Diana, Grisdale, Kathleen, Groves, Morris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Harborside Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4093345/
https://www.ncbi.nlm.nih.gov/pubmed/25031951