Alpha/Beta Interferon Receptor Signaling Amplifies Early Proinflammatory Cytokine Production in the Lung during Respiratory Syncytial Virus Infection

Type I interferons (IFNs) are produced early upon virus infection and signal through the alpha/beta interferon (IFN-α/β) receptor (IFNAR) to induce genes that encode proteins important for limiting viral replication and directing immune responses. To investigate the extent to which type I IFNs play...

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Detalles Bibliográficos
Autores principales: Goritzka, Michelle, Durant, Lydia R., Pereira, Catherine, Salek-Ardakani, Samira, Openshaw, Peter J. M., Johansson, Cecilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2014
Materias:
Cellular Response to Infection
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4093897/
https://www.ncbi.nlm.nih.gov/pubmed/24648449
http://dx.doi.org/10.1128/JVI.00333-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4093897/
https://www.ncbi.nlm.nih.gov/pubmed/24648449
http://dx.doi.org/10.1128/JVI.00333-14

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