Cargando…

Alpha/Beta Interferon Receptor Signaling Amplifies Early Proinflammatory Cytokine Production in the Lung during Respiratory Syncytial Virus Infection

Type I interferons (IFNs) are produced early upon virus infection and signal through the alpha/beta interferon (IFN-α/β) receptor (IFNAR) to induce genes that encode proteins important for limiting viral replication and directing immune responses. To investigate the extent to which type I IFNs play...

Descripción completa

Detalles Bibliográficos
Autores principales:	Goritzka, Michelle, Durant, Lydia R., Pereira, Catherine, Salek-Ardakani, Samira, Openshaw, Peter J. M., Johansson, Cecilia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2014
Materias:	Cellular Response to Infection
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4093897/ https://www.ncbi.nlm.nih.gov/pubmed/24648449 http://dx.doi.org/10.1128/JVI.00333-14

Ejemplares similares

Alpha/Beta Interferon (IFN-α/β) Signaling in Astrocytes Mediates Protection against Viral Encephalomyelitis and Regulates IFN-γ-Dependent Responses
por: Hwang, Mihyun, et al.
Publicado: (2018)

RNase L Amplifies Interferon Signaling by Inducing Protein Kinase R-Mediated Antiviral Stress Granules
por: Manivannan, Praveen, et al.
Publicado: (2020)

Respiratory Syncytial Virus Protects Bystander Cells against Influenza A Virus Infection by Triggering Secretion of Type I and Type III Interferons
por: Czerkies, Maciej, et al.
Publicado: (2022)

Neutrophil-Airway Epithelial Interactions Result in Increased Epithelial Damage and Viral Clearance during Respiratory Syncytial Virus Infection
por: Deng, Yu, et al.
Publicado: (2020)

Activation of the Interferon Induction Cascade by Influenza A Viruses Requires Viral RNA Synthesis and Nuclear Export
por: Killip, Marian J., et al.
Publicado: (2014)

Type III and Not Type I Interferons Efficiently Prevent the Spread of Rotavirus in Human Intestinal Epithelial Cells
por: Doldan, Patricio, et al.
Publicado: (2022)

The Polybasic Cleavage Site in SARS-CoV-2 Spike Modulates Viral Sensitivity to Type I Interferon and IFITM2
por: Winstone, Helena, et al.
Publicado: (2021)

Innate Immune Response to Influenza Virus at Single-Cell Resolution in Human Epithelial Cells Revealed Paracrine Induction of Interferon Lambda 1
por: Ramos, Irene, et al.
Publicado: (2019)

SARS-CoV-2 Triggers an MDA-5-Dependent Interferon Response Which Is Unable To Control Replication in Lung Epithelial Cells
por: Rebendenne, Antoine, et al.
Publicado: (2021)

Lack of Interferon (IFN) Regulatory Factor 8 Associated with Restricted IFN-γ Response Augmented Japanese Encephalitis Virus Replication in the Mouse Brain
por: Tripathi, Aarti, et al.
Publicado: (2021)

Guanylate-Binding Protein 1, an Interferon-Induced GTPase, Exerts an Antiviral Activity against Classical Swine Fever Virus Depending on Its GTPase Activity
por: Li, Lian-Feng, et al.
Publicado: (2016)

Human Hemoglobin Subunit Beta Functions as a Pleiotropic Regulator of RIG-I/MDA5-Mediated Antiviral Innate Immune Responses
por: Yang, Qian, et al.
Publicado: (2019)

Murine Coronavirus Infection Activates the Aryl Hydrocarbon Receptor in an Indoleamine 2,3-Dioxygenase-Independent Manner, Contributing to Cytokine Modulation and Proviral TCDD-Inducible-PARP Expression
por: Grunewald, Matthew E., et al.
Publicado: (2020)

T cell responses are elicited against Respiratory Syncytial Virus in the absence of signalling through TLRs, RLRs and IL-1R/IL-18R
por: Goritzka, Michelle, et al.
Publicado: (2015)

Alveolar Macrophages Can Control Respiratory Syncytial Virus Infection in the Absence of Type I Interferons
por: Makris, Spyridon, et al.
Publicado: (2016)

Chlamydia trachomatis Serovars Drive Differential Production of Proinflammatory Cytokines and Chemokines Depending on the Type of Cell Infected
por: Faris, Robert, et al.
Publicado: (2019)

Enhanced Proinflammatory Cytokine Production and Immunometabolic Impairment of NK Cells Exposed to Mycobacterium tuberculosis and Cigarette Smoke
por: Rao, Yafei, et al.
Publicado: (2022)

Overexpression of proinflammatory cytokines in dental pulp tissue and distinct bacterial microbiota in carious teeth of Mexican Individuals
por: Gómez-García, Ana Pamela, et al.
Publicado: (2022)

Latency-Associated Viral Interleukin-10 (IL-10) Encoded by Human Cytomegalovirus Modulates Cellular IL-10 and CCL8 Secretion during Latent Infection through Changes in the Cellular MicroRNA hsa-miR-92a
por: Poole, Emma, et al.
Publicado: (2014)

MicroRNA-19b-3p Modulates Japanese Encephalitis Virus-Mediated Inflammation via Targeting RNF11
por: Ashraf, Usama, et al.
Publicado: (2016)

Novel Role for Protein Inhibitor of Activated STAT 4 (PIAS4) in the Restriction of Herpes Simplex Virus 1 by the Cellular Intrinsic Antiviral Immune Response
por: Conn, Kristen L., et al.
Publicado: (2016)

Venezuelan Equine Encephalitis Virus Induces Apoptosis through the Unfolded Protein Response Activation of EGR1
por: Baer, Alan, et al.
Publicado: (2016)

Analysis of the Early Immune Response to Infection by Infectious Bursal Disease Virus in Chickens Differing in Their Resistance to the Disease
por: Smith, Jacqueline, et al.
Publicado: (2014)

Feline Calicivirus Infection Disrupts Assembly of Cytoplasmic Stress Granules and Induces G3BP1 Cleavage
por: Humoud, Majid N., et al.
Publicado: (2016)

Notwithstanding Circumstantial Alibis, Cytotoxic T Cells Can Be Major Killers of HIV-1-Infected Cells
por: Gadhamsetty, Saikrishna, et al.
Publicado: (2016)

The PB2 Subunit of the Influenza A Virus RNA Polymerase Is Imported into the Mitochondrial Matrix
por: Long, Joshua C. D., et al.
Publicado: (2016)

Protective Capacity of the Human Anamnestic Antibody Response during Acute Dengue Virus Infection
por: Xu, Meihui, et al.
Publicado: (2016)

Characterization of Human CD8 T Cell Responses in Dengue Virus-Infected Patients from India
por: Chandele, Anmol, et al.
Publicado: (2016)

Herpes Simplex Virus 1 Counteracts Tetherin Restriction via Its Virion Host Shutoff Activity
por: Zenner, Helen L., et al.
Publicado: (2013)

Influenza A Virus Infection in Pigs Attracts Multifunctional and Cross-Reactive T Cells to the Lung
por: Talker, Stephanie C., et al.
Publicado: (2016)

Differential Immunodominance Hierarchy of CD8(+) T-Cell Responses in HLA-B*27:05- and -B*27:02-Mediated Control of HIV-1 Infection
por: Adland, Emily, et al.
Publicado: (2018)

Asian Elephant T Cell Responses to Elephant Endotheliotropic Herpesvirus
por: Fuery, Angela, et al.
Publicado: (2018)

H5N1 Influenza A Virus PB1-F2 Relieves HAX-1-Mediated Restriction of Avian Virus Polymerase PA in Human Lung Cells
por: Mazel-Sanchez, B., et al.
Publicado: (2018)

Dose of Retroviral Infection Determines Induction of Antiviral NK Cell Responses
por: Littwitz-Salomon, Elisabeth, et al.
Publicado: (2017)

Viperin Targets Flavivirus Virulence by Inducing Assembly of Noninfectious Capsid Particles
por: Vonderstein, Kirstin, et al.
Publicado: (2017)

Tumor Necrosis Factor-Mediated Survival of CD169(+) Cells Promotes Immune Activation during Vesicular Stomatitis Virus Infection
por: Shinde, Prashant V., et al.
Publicado: (2018)

The Human CD4(+) T Cell Response against Mumps Virus Targets a Broadly Recognized Nucleoprotein Epitope
por: de Wit, Jelle, et al.
Publicado: (2019)

DUSP10 Negatively Regulates the Inflammatory Response to Rhinovirus through Interleukin-1β Signaling
por: Manley, Grace C. A., et al.
Publicado: (2019)

Dynamics of Virus-Specific Memory B Cells and Plasmablasts following Viral Infection of the Central Nervous System
por: Atkinson, Jeffrey R., et al.
Publicado: (2019)

Porcine Reproductive and Respiratory Syndrome Virus Activates Lipophagy To Facilitate Viral Replication through Downregulation of NDRG1 Expression
por: Wang, Jiang, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_1mp6s2kv9p08hee90ur8g0cu9b