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Intraperitoneal Administration of a Tumor-Associated Antigen SART3, CD40L, and GM-CSF Gene-Loaded Polyplex Micelle Elicits a Vaccine Effect in Mouse Tumor Models

Polyplex micelles have demonstrated biocompatibility and achieve efficient gene transfection in vivo. Here, we investigated a polyplex micelle encapsulating genes encoding the tumor-associated antigen squamous cell carcinoma antigen recognized by T cells-3 (SART3), adjuvant CD40L, and granulocyte ma...

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Detalles Bibliográficos
Autores principales: Furugaki, Kouichi, Cui, Lin, Kunisawa, Yumi, Osada, Kensuke, Shinkai, Kentaro, Tanaka, Masao, Kataoka, Kazunori, Nakano, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094388/
https://www.ncbi.nlm.nih.gov/pubmed/25013909
http://dx.doi.org/10.1371/journal.pone.0101854