Prediction of kinase inhibitor response using activity profiling, in vitro screening, and elastic net regression

BACKGROUND: Many kinase inhibitors have been approved as cancer therapies. Recently, libraries of kinase inhibitors have been extensively profiled, thus providing a map of the strength of action of each compound on a large number of its targets. These profiled libraries define drug-kinase networks t...

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Detalles Bibliográficos
Autores principales: Tran, Trish P, Ong, Edison, Hodges, Andrew P, Paternostro, Giovanni, Piermarocchi, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094402/
https://www.ncbi.nlm.nih.gov/pubmed/24961498
http://dx.doi.org/10.1186/1752-0509-8-74

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094402/
https://www.ncbi.nlm.nih.gov/pubmed/24961498
http://dx.doi.org/10.1186/1752-0509-8-74

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