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Prediction of kinase inhibitor response using activity profiling, in vitro screening, and elastic net regression
BACKGROUND: Many kinase inhibitors have been approved as cancer therapies. Recently, libraries of kinase inhibitors have been extensively profiled, thus providing a map of the strength of action of each compound on a large number of its targets. These profiled libraries define drug-kinase networks t...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094402/ https://www.ncbi.nlm.nih.gov/pubmed/24961498 http://dx.doi.org/10.1186/1752-0509-8-74 |