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Systemic Treatment with Erythropoietin Protects the Neurovascular Unit in a Rat Model of Retinal Neurodegeneration

Rats expressing a transgenic polycystic kidney disease (PKD) gene develop photoreceptor degeneration and subsequent vasoregression, as well as activation of retinal microglia and macroglia. To target the whole neuroglialvascular unit, neuro- and vasoprotective Erythropoietin (EPO) was intraperitonea...

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Detalles Bibliográficos
Autores principales: Busch, Stephanie, Kannt, Aimo, Kolibabka, Matthias, Schlotterer, Andreas, Wang, Qian, Lin, Jihong, Feng, Yuxi, Hoffmann, Sigrid, Gretz, Norbert, Hammes, Hans-Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094460/
https://www.ncbi.nlm.nih.gov/pubmed/25013951
http://dx.doi.org/10.1371/journal.pone.0102013