A Water-Soluble Inclusion Complex of Pedunculoside with the Polymer β-Cyclodextrin: A Novel Anti-Inflammation Agent with Low Toxicity

More than 50% of new drug candidates in drug discovery are lipophilic and exhibit poor aqueous solubility, which results in poor bioavailability and a lack of dose proportionality. Here, we improved the solubility of pedunculoside (PE) by generating a water-soluble inclusion complex composed of PE a...

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Detalles Bibliográficos
Autores principales: Liu, Chang, Zhang, Wang, Yang, Hao, Sun, Weidong, Gong, Xiangdong, Zhao, Junxian, Sun, Yun, Diao, Guowang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094462/
https://www.ncbi.nlm.nih.gov/pubmed/25013908
http://dx.doi.org/10.1371/journal.pone.0101761

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094462/
https://www.ncbi.nlm.nih.gov/pubmed/25013908
http://dx.doi.org/10.1371/journal.pone.0101761

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