Heritable Genome Editing with CRISPR/Cas9 in the Silkworm, Bombyx mori

We report the establishment of an efficient and heritable gene mutagenesis method in the silkworm Bombyx mori using modified type II clustered regularly interspaced short palindromic repeats (CRISPR) with an associated protein (Cas9) system. Using four loci Bm-ok, BmKMO, BmTH, and Bmtan as candidate...

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Detalles Bibliográficos
Autores principales: Wei, Wei, Xin, Huhu, Roy, Bhaskar, Dai, Junbiao, Miao, Yungen, Gao, Guanjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094479/
https://www.ncbi.nlm.nih.gov/pubmed/25013902
http://dx.doi.org/10.1371/journal.pone.0101210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094479/
https://www.ncbi.nlm.nih.gov/pubmed/25013902
http://dx.doi.org/10.1371/journal.pone.0101210

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