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Post-Transcriptional Regulation of BCL2 mRNA by the RNA-Binding Protein ZFP36L1 in Malignant B Cells

The human ZFP36 zinc finger protein family consists of ZFP36, ZFP36L1, and ZFP36L2. These proteins regulate various cellular processes, including cell apoptosis, by binding to adenine uridine rich elements in the 3′ untranslated regions of sets of target mRNAs to promote their degradation. The pro-a...

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Detalles Bibliográficos
Autores principales: Zekavati, Anna, Nasir, Asghar, Alcaraz, Amor, Aldrovandi, Maceler, Marsh, Phil, Norton, John D., Murphy, John J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094554/
https://www.ncbi.nlm.nih.gov/pubmed/25014217
http://dx.doi.org/10.1371/journal.pone.0102625