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Suppression of PAX6 promotes cell proliferation and inhibits apoptosis in human retinoblastoma cells

The aim of this study was to investigate the role of the transcription factor, PAX6, in the development of retinoblastoma. The expression of endogenous PAX6 was knocked down using PAX6-specific lentivirus in two human retinoblastoma cell lines, SO-Rb50 and Y79. Cell proliferation functional assays a...

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Detalles Bibliográficos
Autores principales: MENG, BO, WANG, YISONG, LI, BIN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094585/
https://www.ncbi.nlm.nih.gov/pubmed/24939714
http://dx.doi.org/10.3892/ijmm.2014.1812