Genotoxicity evaluation of Guibi-Tang extract using an in vitro bacterial reverse mutation assay, chromosome aberration assay, and in vivo micronucleus test

BACKGROUND: Guibi-Tang is a traditional herbal prescription made from 12 different herbs that is used in the treatment of amnesia and poor memory. METHODS: In the present study, we evaluated the acute oral toxicity and genotoxic potential of Guibi-Tang water extract (GBT) at doses up to 2000 μg/plat...

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Detalles Bibliográficos
Autores principales: Lee, Mee-Young, Seo, Chang-Seob, Kim, Ji-Young, Shin, Hyeun-Kyoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094639/
https://www.ncbi.nlm.nih.gov/pubmed/24985139
http://dx.doi.org/10.1186/1472-6882-14-215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094639/
https://www.ncbi.nlm.nih.gov/pubmed/24985139
http://dx.doi.org/10.1186/1472-6882-14-215

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