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Genotoxicity evaluation of Guibi-Tang extract using an in vitro bacterial reverse mutation assay, chromosome aberration assay, and in vivo micronucleus test

BACKGROUND: Guibi-Tang is a traditional herbal prescription made from 12 different herbs that is used in the treatment of amnesia and poor memory. METHODS: In the present study, we evaluated the acute oral toxicity and genotoxic potential of Guibi-Tang water extract (GBT) at doses up to 2000 μg/plat...

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Detalles Bibliográficos
Autores principales:	Lee, Mee-Young, Seo, Chang-Seob, Kim, Ji-Young, Shin, Hyeun-Kyoo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094639/ https://www.ncbi.nlm.nih.gov/pubmed/24985139 http://dx.doi.org/10.1186/1472-6882-14-215

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