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Trends in drug resistance codons in Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase genes in Kenyan parasites from 2008 to 2012

BACKGROUND: Sulphadoxine-pyrimethamine (SP), an antifolate, was replaced by artemether-lumefantrine as the first-line malaria drug treatment in Kenya in 2004 due to the wide spread of resistance. However, SP still remains the recommended drug for intermittent preventive treatment in pregnant women a...

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Detalles Bibliográficos
Autores principales: Juma, Dennis W, Omondi, Angela A, Ingasia, Luiser, Opot, Benjamin, Cheruiyot, Agnes, Yeda, Redemptah, Okudo, Charles, Cheruiyot, Jelagat, Muiruri, Peninnah, Ngalah, Bidii, Chebon, Lorna J, Eyase, Fredrick, Johnson, Jacob, Bulimo, Wallace D, Akala, Hoseah M, Andagalu, Ben, Kamau, Edwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094641/
https://www.ncbi.nlm.nih.gov/pubmed/24989984
http://dx.doi.org/10.1186/1475-2875-13-250