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Matrix Metalloproteinases and Their Multiple Roles in Alzheimer's Disease

Alzheimer's disease (AD) is the most prevalent type of dementia. Pathological changes in the AD brain include amyloid-β (Aβ) plaques and neurofibrillary tangles (NFTs), as well as neuronal death and synaptic loss. Matrix metalloproteinases (MMPs) play an important role as inflammatory component...

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Detalles Bibliográficos
Autores principales: Wang, Xiang-Xiang, Tan, Meng-Shan, Yu, Jin-Tai, Tan, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094696/
https://www.ncbi.nlm.nih.gov/pubmed/25050378
http://dx.doi.org/10.1155/2014/908636