Cargando…

Liquiritin modulates ERK- and AKT/GSK-3β-dependent pathways to protect against glutamate-induced cell damage in differentiated PC12 cells

Glutamate has a key role in the neuronal cell damage associated with Alzheimer’s and Parkinson’s diseases. Liquiritin (LQ), a major constituent of Glycyrrhiza Radix, possesses various pharmacological activities. The present study investigated the neuroprotective effect of LQ against glutamate-induce...

Descripción completa

Detalles Bibliográficos
Autores principales: TENG, LESHENG, MENG, QINGFAN, LU, JIAHUI, XIE, JING, WANG, ZHENZUO, LIU, YAN, WANG, DI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094771/
https://www.ncbi.nlm.nih.gov/pubmed/24888902
http://dx.doi.org/10.3892/mmr.2014.2289