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Allosteric inhibition of a stem cell RNA-binding protein by an intermediary metabolite
Gene expression and metabolism are coupled at numerous levels. Cells must sense and respond to nutrients in their environment, and specialized cells must synthesize metabolic products required for their function. Pluripotent stem cells have the ability to differentiate into a wide variety of special...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094780/ https://www.ncbi.nlm.nih.gov/pubmed/24935936 http://dx.doi.org/10.7554/eLife.02848 |