Allosteric inhibition of a stem cell RNA-binding protein by an intermediary metabolite

Gene expression and metabolism are coupled at numerous levels. Cells must sense and respond to nutrients in their environment, and specialized cells must synthesize metabolic products required for their function. Pluripotent stem cells have the ability to differentiate into a wide variety of special...

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Detalles Bibliográficos
Autores principales: Clingman, Carina C, Deveau, Laura M, Hay, Samantha A, Genga, Ryan M, Shandilya, Shivender MD, Massi, Francesca, Ryder, Sean P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094780/
https://www.ncbi.nlm.nih.gov/pubmed/24935936
http://dx.doi.org/10.7554/eLife.02848

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094780/
https://www.ncbi.nlm.nih.gov/pubmed/24935936
http://dx.doi.org/10.7554/eLife.02848

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