miR-16-1 Promotes the Aberrant α-Synuclein Accumulation in Parkinson Disease via Targeting Heat Shock Protein 70

There is striking evidence that heat shock protein 70 (Hsp70) negatively regulates α-synuclein aggregation, which plays a significant role in the formation and progression of Parkinson disease (PD). However, how the Hsp70 in neurons fails to prevent or even reverse α-synuclein aggregation and toxici...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Zhelin, Cheng, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094852/
https://www.ncbi.nlm.nih.gov/pubmed/25054189
http://dx.doi.org/10.1155/2014/938348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094852/
https://www.ncbi.nlm.nih.gov/pubmed/25054189
http://dx.doi.org/10.1155/2014/938348

Ejemplares similares