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Simultaneous Changes of Spatial Memory and Spine Density after Intrahippocampal Administration of Fibrillar Aβ (1–42) to the Rat Brain

Several animal models of Alzheimer's disease have been used in laboratory experiments. Intrahippocampal injection of fibrillar amyloid-beta (fAβ) peptide represents one of the most frequently used models, mimicking Aβ deposits in the brain. In our experiment synthetic fAβ (1–42) peptide was adm...

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Detalles Bibliográficos
Autores principales: Borbély, Emőke, Horváth, János, Furdan, Szabina, Bozsó, Zsolt, Penke, Botond, Fülöp, Lívia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094878/
https://www.ncbi.nlm.nih.gov/pubmed/25050342
http://dx.doi.org/10.1155/2014/345305