Cargando…
Simultaneous Changes of Spatial Memory and Spine Density after Intrahippocampal Administration of Fibrillar Aβ (1–42) to the Rat Brain
Several animal models of Alzheimer's disease have been used in laboratory experiments. Intrahippocampal injection of fibrillar amyloid-beta (fAβ) peptide represents one of the most frequently used models, mimicking Aβ deposits in the brain. In our experiment synthetic fAβ (1–42) peptide was adm...
Autores principales: | Borbély, Emőke, Horváth, János, Furdan, Szabina, Bozsó, Zsolt, Penke, Botond, Fülöp, Lívia |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094878/ https://www.ncbi.nlm.nih.gov/pubmed/25050342 http://dx.doi.org/10.1155/2014/345305 |
Ejemplares similares
-
Impact of Two Neuronal Sigma-1 Receptor Modulators, PRE084 and DMT, on Neurogenesis and Neuroinflammation in an Aβ(1–42)-Injected, Wild-Type Mouse Model of AD
por: Borbély, Emőke, et al.
Publicado: (2022) -
Effects of the Pentapeptide P33 on Memory and Synaptic Plasticity in APP/PS1 Transgenic Mice: A Novel Mechanism Presenting the Protein Fe65 as a Target
por: Szögi, Titanilla, et al.
Publicado: (2019) -
Examination of Longitudinal Alterations in Alzheimer’s Disease-Related Neurogenesis in an APP/PS1 Transgenic Mouse Model, and the Effects of P33, a Putative Neuroprotective Agent Thereon
por: Szögi, Titanilla, et al.
Publicado: (2022) -
Abeta(1-42) Enhances Neuronal Excitability in the CA1 via NR2B Subunit-Containing NMDA Receptors
por: Varga, Edina, et al.
Publicado: (2014) -
Studies for Improving a Rat Model of Alzheimer’s Disease: Icv Administration of Well-Characterized β-Amyloid 1-42 Oligomers Induce Dysfunction in Spatial Memory
por: Kasza, Ágnes, et al.
Publicado: (2017)