A High-Content RNAi Screen Identifies Ubiquitin Modifiers That Regulate TNF-Dependent Nuclear Accumulation of NF-κB

The mammalian tumor necrosis factor (TNF) cytokine is a central mediator of inflammatory events. Recent studies revealed a number of complex and sophisticated interactions between the TNF pathway and the enzymatic activities encoded by ubiquitin ligases and deubiquitylation enzymes. However, very li...

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Detalles Bibliográficos
Autores principales: Fraser, Brittany, Maranchuk, Robert A., Foley, Edan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094887/
https://www.ncbi.nlm.nih.gov/pubmed/25071782
http://dx.doi.org/10.3389/fimmu.2014.00322

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094887/
https://www.ncbi.nlm.nih.gov/pubmed/25071782
http://dx.doi.org/10.3389/fimmu.2014.00322

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