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A High-Content RNAi Screen Identifies Ubiquitin Modifiers That Regulate TNF-Dependent Nuclear Accumulation of NF-κB

The mammalian tumor necrosis factor (TNF) cytokine is a central mediator of inflammatory events. Recent studies revealed a number of complex and sophisticated interactions between the TNF pathway and the enzymatic activities encoded by ubiquitin ligases and deubiquitylation enzymes. However, very li...

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Detalles Bibliográficos
Autores principales:	Fraser, Brittany, Maranchuk, Robert A., Foley, Edan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094887/ https://www.ncbi.nlm.nih.gov/pubmed/25071782 http://dx.doi.org/10.3389/fimmu.2014.00322

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