Polygenic Scores Predict Alcohol Problems in an Independent Sample and Show Moderation by the Environment

Alcohol problems represent a classic example of a complex behavioral outcome that is likely influenced by many genes of small effect. A polygenic approach, which examines aggregate measured genetic effects, can have predictive power in cases where individual genes or genetic variants do not. In the...

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Detalles Bibliográficos
Autores principales: Salvatore, Jessica E., Aliev, Fazil, Edwards, Alexis C., Evans, David M., Macleod, John, Hickman, Matthew, Lewis, Glyn, Kendler, Kenneth S., Loukola, Anu, Korhonen, Tellervo, Latvala, Antti, Rose, Richard J., Kaprio, Jaakko, Dick, Danielle M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094936/
https://www.ncbi.nlm.nih.gov/pubmed/24727307
http://dx.doi.org/10.3390/genes5020330

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094936/
https://www.ncbi.nlm.nih.gov/pubmed/24727307
http://dx.doi.org/10.3390/genes5020330

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