Adult tissue methylomes harbor epigenetic memory at embryonic enhancers

Mammalian development requires cytosine methylation, a heritable epigenetic mark of cellular memory believed to maintain a cell’s unique gene expression pattern. However, it remains unclear how dynamic DNA methylation relates to cell-type specific gene expression and animal development. Here, by map...

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Detalles Bibliográficos
Autores principales: Hon, Gary C., Rajagopal, Nisha, Shen, Yin, McCleary, David F., Yue, Feng, Dang, My D., Ren, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4095776/
https://www.ncbi.nlm.nih.gov/pubmed/23995138
http://dx.doi.org/10.1038/ng.2746

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4095776/
https://www.ncbi.nlm.nih.gov/pubmed/23995138
http://dx.doi.org/10.1038/ng.2746

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