Absence of γ-sarcoglycan alters the response of p70S6 kinase to mechanical perturbation in murine skeletal muscle

BACKGROUND: The dystrophin glycoprotein complex (DGC) is located at the sarcolemma of muscle fibers, providing structural integrity. Mutations in and loss of DGC proteins cause a spectrum of muscular dystrophies. When only the sarcoglycan subcomplex is absent, muscles display severe myofiber degener...

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Detalles Bibliográficos
Autores principales: Moorwood, Catherine, Philippou, Anastassios, Spinazzola, Janelle, Keyser, Benjamin, Macarak, Edward J, Barton, Elisabeth R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4095884/
https://www.ncbi.nlm.nih.gov/pubmed/25024843
http://dx.doi.org/10.1186/2044-5040-4-13

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4095884/
https://www.ncbi.nlm.nih.gov/pubmed/25024843
http://dx.doi.org/10.1186/2044-5040-4-13

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