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Absence of γ-sarcoglycan alters the response of p70S6 kinase to mechanical perturbation in murine skeletal muscle
BACKGROUND: The dystrophin glycoprotein complex (DGC) is located at the sarcolemma of muscle fibers, providing structural integrity. Mutations in and loss of DGC proteins cause a spectrum of muscular dystrophies. When only the sarcoglycan subcomplex is absent, muscles display severe myofiber degener...
Autores principales: | Moorwood, Catherine, Philippou, Anastassios, Spinazzola, Janelle, Keyser, Benjamin, Macarak, Edward J, Barton, Elisabeth R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4095884/ https://www.ncbi.nlm.nih.gov/pubmed/25024843 http://dx.doi.org/10.1186/2044-5040-4-13 |
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