Addition of a Second Binding Site Increases the Dynamic Range but Alters the Cellular Localization of a Red Fluorescent Probe for Mobile Zinc

[Image: see text] We report the synthesis and photophysical properties of ZBR4 and ZR1, two resorufin-based ditopic probes for mobile zinc. Upon binding Zn(2+), the sensors display 14- and 41-fold enhancements of their red fluorescence emission, respectively. In contrast to ZR1 and other members of...

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Detalles Bibliográficos
Autores principales: Loas, Andrei, Radford, Robert J., Lippard, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4095928/
https://www.ncbi.nlm.nih.gov/pubmed/24915285
http://dx.doi.org/10.1021/ic500732z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4095928/
https://www.ncbi.nlm.nih.gov/pubmed/24915285
http://dx.doi.org/10.1021/ic500732z

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