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Oxygen Pathways and Allostery in Monomeric Sarcosine Oxidase via Single-Sweep Free-Energy Reconstruction

[Image: see text] Monomeric sarcosine oxidase (MSOX) is a flavoprotein D-amino acid oxidase with reported sarcosine and oxygen activation sites on the re and si faces of the flavin ring, respectively. O(2) transport routes to the catalytic interior are not well understood and are difficult to ascert...

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Detalles Bibliográficos
Autores principales: Bucci, Anthony, Abrams, Cameron F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4095932/
https://www.ncbi.nlm.nih.gov/pubmed/25061440
http://dx.doi.org/10.1021/ct500088z