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Exploring the Role of Conformational Heterogeneity in cis-Autoproteolytic Activation of ThnT

[Image: see text] In the past decade, there have been major achievements in understanding the relationship between enzyme catalysis and protein structural plasticity. In autoprocessing systems, however, there is a sparsity of direct evidence of the role of conformational dynamics, which are complica...

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Detalles Bibliográficos
Autores principales: Buller, Andrew R., Freeman, Michael F., Schildbach, Joel F., Townsend, Craig A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4095933/
https://www.ncbi.nlm.nih.gov/pubmed/24933323
http://dx.doi.org/10.1021/bi500385d