The transcription factor Pou3f1 promotes neural fate commitment via activation of neural lineage genes and inhibition of external signaling pathways

The neural fate commitment of pluripotent stem cells requires the repression of extrinsic inhibitory signals and the activation of intrinsic positive transcription factors. However, how these two events are integrated to ensure appropriate neural conversion remains unclear. In this study, we showed...

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Detalles Bibliográficos
Autores principales: Zhu, Qingqing, Song, Lu, Peng, Guangdun, Sun, Na, Chen, Jun, Zhang, Ting, Sheng, Nengyin, Tang, Wei, Qian, Cheng, Qiao, Yunbo, Tang, Ke, Han, Jing-Dong Jackie, Li, Jinsong, Jing, Naihe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Developmental Biology and Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4095939/
https://www.ncbi.nlm.nih.gov/pubmed/24929964
http://dx.doi.org/10.7554/eLife.02224

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4095939/
https://www.ncbi.nlm.nih.gov/pubmed/24929964
http://dx.doi.org/10.7554/eLife.02224

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