Suppression of the Oncogenic Transcription Factor FOXM1 by Proteasome Inhibitors

The oncogenic transcription factor FOXM1 is one of the key regulators of tumorigenesis. We found that FOXM1 upregulates its own transcription and its protein stability depends on its interaction with the chaperone nucleophosmin. We also determined that FOXM1 is negatively regulated by the tumor supp...

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Detalles Bibliográficos
Autor principal: Gartel, Andrei L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4095980/
https://www.ncbi.nlm.nih.gov/pubmed/25093142
http://dx.doi.org/10.1155/2014/596528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4095980/
https://www.ncbi.nlm.nih.gov/pubmed/25093142
http://dx.doi.org/10.1155/2014/596528

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