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In Silico Investigation of Potential TRAF6 Inhibitor from Traditional Chinese Medicine against Cancers

It has been indicated that tumor necrosis factor receptor-associated factor-6 (TRAF6) will upregulate the expression of hypoxia-inducible factor-1α (HIF-1α) and promote tumor angiogenesis. TRAF6 proteins can be treated as drug target proteins for a differentiation therapy against cancers. As structu...

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Detalles Bibliográficos
Autores principales: Chen, Kuan-Chung, Lee, Wen-Yuan, Chen, Hsin-Yi, Chen, Calvin Yu-Chian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096009/
https://www.ncbi.nlm.nih.gov/pubmed/25089269
http://dx.doi.org/10.1155/2014/429486