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Bioinformatic and Proteomic Analysis of Bulk Histones Reveals PTM Crosstalk and Chromatin Features

[Image: see text] Systems analysis of chromatin has been constrained by complex patterns and dynamics of histone post-translational modifications (PTMs), which represent major challenges for both mass spectrometry (MS) and immuno-based approaches (e.g., chromatin immuno-precipitation, ChIP). Here we...

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Detalles Bibliográficos
Autores principales: Zhang, Chunchao, Gao, Shan, Molascon, Anthony J., Wang, Zhe, Gorovsky, Martin A., Liu, Yifan, Andrews, Philip C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096215/
https://www.ncbi.nlm.nih.gov/pubmed/24894457
http://dx.doi.org/10.1021/pr5001829