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MMP-9 Responsive PEG Cleavable Nanovesicles for Efficient Delivery of Chemotherapeutics to Pancreatic Cancer

[Image: see text] Significant differences in biochemical parameters between normal and tumor tissues offer an opportunity to chemically design drug carriers which respond to these changes and deliver the drugs at the desired site. For example, overexpression of the matrix metalloproteinase-9 (MMP-9)...

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Detalles Bibliográficos
Autores principales: Kulkarni, Prajakta S., Haldar, Manas K., Nahire, Rahul R., Katti, Preeya, Ambre, Avinash H., Muhonen, Wallace W., Shabb, John B., Padi, Sathish K. R., Singh, Raushan K., Borowicz, Pawel P., Shrivastava, D. K., Katti, Kalpana S., Reindl, Katie, Guo, Bin, Mallik, Sanku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096225/
https://www.ncbi.nlm.nih.gov/pubmed/24827725
http://dx.doi.org/10.1021/mp500108p