Cognition and Hippocampal Plasticity in the Mouse Is Altered by Monosomy of a Genomic Region Implicated in Down Syndrome

Down syndrome (DS) is due to increased copy number of human chromosome 21. The contribution of different genetic regions has been tested using mouse models. As shown previously, the Abcg1-U2af1 genetic region contributes to cognitive defects in working and short-term recognition memory in Down syndr...

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Detalles Bibliográficos
Autores principales: Sahún, Ignasi, Marechal, Damien, Pereira, Patricia Lopes, Nalesso, Valérie, Gruart, Agnes, Garcia, José Maria Delgado, Antonarakis, Stylianos E., Dierssen, Mara, Herault, Yann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2014
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096369/
https://www.ncbi.nlm.nih.gov/pubmed/24752061
http://dx.doi.org/10.1534/genetics.114.165241

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096369/
https://www.ncbi.nlm.nih.gov/pubmed/24752061
http://dx.doi.org/10.1534/genetics.114.165241

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