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In Silico Investigation of Potential Pyruvate Kinase M2 Regulators from Traditional Chinese Medicine against Cancers

A recent research in cancer research demonstrates that tumor-specific pyruvate kinase M2 (PKM2) plays an important role in chromosome segregation and mitosis progression of tumor cells. To improve the drug development of TCM compounds, we aim to identify potent TCM compounds as lead compounds of PKM...

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Detalles Bibliográficos
Autores principales: Chen, Kuan-Chung, Chen, Kuen-Bao, Chen, Hsin-Yi, Chen, Calvin Yu-Chian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096393/
https://www.ncbi.nlm.nih.gov/pubmed/25089263
http://dx.doi.org/10.1155/2014/189495