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Qualitative and Quantitative Comparison of the Proteome of Erythroid Cells Differentiated from Human iPSCs and Adult Erythroid Cells by Multiplex TMT Labelling and NanoLC-MS/MS

Induced pluripotent stem cells (iPSC) are an attractive progenitor source for the generation of in vitro blood products. However, before iPSC-derived erythroid cells can be considered for therapeutic use their similarity to adult erythroid cells must be confirmed. We have analysed the proteome of er...

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Detalles Bibliográficos
Autores principales: Trakarnsanga, Kongtana, Wilson, Marieangela C., Griffiths, Rebecca E., Toye, Ashley M., Carpenter, Lee, Heesom, Kate J., Parsons, Steve F., Anstee, David J., Frayne, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096399/
https://www.ncbi.nlm.nih.gov/pubmed/25019302
http://dx.doi.org/10.1371/journal.pone.0100874