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TRPC6 Single Nucleotide Polymorphisms and Progression of Idiopathic Membranous Nephropathy
BACKGROUND: Activating mutations in the Transient Receptor Potential channel C6 (TRPC6) cause autosomal dominant focal segmental glomerular sclerosis (FSGS). TRPC6 expression is upregulated in renal biopsies of patients with idiopathic membranous glomerulopathy (iMN) and animal models thereof. In iM...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096511/ https://www.ncbi.nlm.nih.gov/pubmed/25019165 http://dx.doi.org/10.1371/journal.pone.0102065 |