Cargando…
TRPC6 Single Nucleotide Polymorphisms and Progression of Idiopathic Membranous Nephropathy
BACKGROUND: Activating mutations in the Transient Receptor Potential channel C6 (TRPC6) cause autosomal dominant focal segmental glomerular sclerosis (FSGS). TRPC6 expression is upregulated in renal biopsies of patients with idiopathic membranous glomerulopathy (iMN) and animal models thereof. In iM...
Autores principales: | Hofstra, Julia M., Coenen, Marieke J. H., Schijvenaars, Mascha M. V. A. P., Berden, Jo H. M., van der Vlag, Johan, Hoefsloot, Lies H., Knoers, Nine V. A. M., Wetzels, Jack F. M., Nijenhuis, Tom |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096511/ https://www.ncbi.nlm.nih.gov/pubmed/25019165 http://dx.doi.org/10.1371/journal.pone.0102065 |
Ejemplares similares
-
A Putative Role for TRPC6 in Immune-Mediated Kidney Injury
por: ‘t Hart, Daan C., et al.
Publicado: (2023) -
Synthetic ACTH in High Risk Patients with Idiopathic Membranous Nephropathy: A Prospective, Open Label Cohort Study
por: van de Logt, Anne-Els, et al.
Publicado: (2015) -
Repurposing Riociguat to Target a Novel Paracrine Nitric Oxide-TRPC6 Pathway to Prevent Podocyte Injury
por: ‘t Hart, Daan, et al.
Publicado: (2021) -
Ancestral Origin of the First Indian Families with Myotonic Dystrophy Type 2
por: Damen, Manon, et al.
Publicado: (2021) -
Current insights into renal ciliopathies: what can genetics teach us?
por: Arts, Heleen H., et al.
Publicado: (2012)