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CXCR3 modulates glial accumulation and activation in cuprizone-induced demyelination of the central nervous system

BACKGROUND: The functional state of glial cells, like astrocytes and microglia, critically modulates the course of neuroinflammatory and neurodegenerative diseases and can have both detrimental and beneficial effects. Glial cell function is tightly controlled by cellular interactions in which cytoki...

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Detalles Bibliográficos
Autores principales: Krauthausen, Marius, Saxe, Simon, Zimmermann, Julian, Emrich, Michael, Heneka, Michael T, Müller, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096537/
https://www.ncbi.nlm.nih.gov/pubmed/24930935
http://dx.doi.org/10.1186/1742-2094-11-109